WebSep 1, 1980 · The results from 5 patients gave a range of 54 to 173 ng of thioinosinic acid per 5 x 10(6) lymphocytes, with a mean of 110 ng. 4 In an in vitro incubation of azathioprine, 1mM with fresh human blood, 160 and 180 ng of thioinosinic acid per 5 x 10(6) lymphocytes was formed after 0.5 h and 5 h respectively. 5 The assay is suitable for the study ... Web1 A specific assay for the measurement of thioinosinic acid, in human lymphocytes, has been developed with a sensitivity of 50 ng of thioinosinic acid per 5 x 10(6) lymphocytes. …
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WebDec 25, 1987 · Abstract. A highly sensitive reversed-phase high-performance liquid chromatographic assay, with ultraviolet detection, for 6-thioinosinic acid and the 6 … WebJul 1, 1982 · Poly(6‐thioinosinic acid), poly(s6I), a synthetic polynucleotide shown to inhibit L1210 ascites growth in vivo, was compared with 6‐mercaptopurine (6‐MP) for their effects on cellular kinetics of L1210 cells in vitro. These kinetic perturbations were monitored by changes in growth rates, cell volumes and cell‐cycle distributions. At equimolar exposure … lwrc 5.56
Assay of thioinosinic acid, an active metabolite of azathioprine, in ...
WebThe results from 5 patients gave a range of 54 to 173 ng of thioinosinic acid per 5 × 10(6) lymphocytes, with a mean of 110 ng. 4 In an in vitro incubation of azathioprine, 1mM with fresh human blood, 160 and 180 ng of thioinosinic acid per 5 × 10(6) lymphocytes was formed after 0.5 h and 5 h respectively. 5 The assay is suitable for the ... WebAzathioprine is a prodrug, converted to the active metabolites 6-mercaptopurine and 6-thioinosinic acid. It replaced 6-mercaptopurine as an immunosuppressive treatment for … WebSuppliers List, E-mail/RFQ Form, Molecular Structure, Weight, Formula, IUPAC, Synonyms for POLY(THIOINOSINIC ACID) (CAS No. 59126-38-4) Skype. POLY(THIOINOSINIC ACID) (CAS No. 59126-38-4) Suppliers EMAIL INQUIRY to 1 suppliers . SAGECHEM LIMITED Address: Room C1301, New Youth Plaza, NO.8 Jia Shan Road, Hangzhou, Zhejiang 310014, China kings norton refuse centre