Phospho irf7
WebPhospho-IRF7 (Ser437/438) IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role … WebMethods: We evaluated the immunohistochemical (IHC) expression of Toll-like receptors 3-7-8-9 (TLR-3-7-8-9), TIR domain-containing adaptor inducing IFNβ (TRIF), Interferon regulatory factor 3 (IRF3), Phospho interferon regulatory factor 3 (pIRF3), Interferon regulatory factor 7 (IRF7), Phospho interferon regulatory factor 7 (pIRF7), retinoic ...
Phospho irf7
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WebDescription: HEK-EBNA cells were fixed and permeabilized using the Cell Signaling Buffer Set A. Cells were then stained with Anti-IRF-7 antibodies or with the corresponding REA … WebFeb 21, 2024 · IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling.
WebDec 30, 2013 · As shown in Fig. 2 D, the MC160 protein prevented IRF7 activation because phospho-IRF7 levels were greatly diminished in MC160-expressing cells versus vector-transfected cells. In contrast, the MC159 protein did not inhibit IRF7 activation under these conditions: phospho-IRF7 levels were similar in pMC159- versus pCI-transfected cells. WebClone REA310 recognizes the interferon regulatory factor 7 (IRF-7) phosphorylated at serines 477 and 479 (pS477/pS479). IRF-7 is a member of the IRF family of transcription factors and a key player in the innate immune response against viral infections. Constitutive expression of IRF-7 is limited to peripheral blood lymphocytes and dendritic cells while in …
WebAnti-Phospho-IRF7-S471/472 Antibody from Assay Genie is a high quality antibody with reactivity against Human, Mouse and validated in WB applications. Toggle menu Select Currency: EUR WebMar 29, 2024 · The juxtaposition of both the ubiquitination site and phospho-acceptor site on IRF7 and other IRFs suggests that such these post-translational modifications work sequentially to recruit in all the players necessary for activation. And similar to STING, it appears that competing ubiquitin or ubiquitin-like modifications work to fine-tune and ...
WebSep 16, 2024 · The mice were intraperitoneally administrated with 100 mg fucoidan at 0, 1, 3, 5, and 7 days post-infection. e Phospho-ERK, total ERK, phospho-IRF7, and total IRF7 in the liver tissue of infected mice were examined by western blotting at the indicated days post-infection. f The production of IFN-α in the serum was evaluated by ELISA analysis. * p …
WebNov 29, 2024 · IFN-I is the key regulatory component activating and modulating the response of innate and adaptive immune system to bacterial as well as viral pathogens. IFN-I promotes the expression of IFN-induced genes (ISG) and, consequently, the production of chemokines, e.g., CXCL10. Those chemokines control migration and localization of … inbox by gmail notificationsWebSep 1, 2024 · Irf3-/-Irf7-/- MEFs were seeded on 24-well plates (1 ×10 5 cells/well) and transfected the following day with 50 ng of luciferase reporter plasmid together with 0.8 μg of expression plasmid or empty control plasmid via Lipofectamine 2000 (Invitrogen). inciweb inapWebBuy Anti-phospho-IRF7 (Ser471/472), item number: G-CABP1264.20 from Assay Genie at Biomol! Protein function: Key transcriptional regulator of type I interferon (IFN)- dependent … inbox chairWebJan 3, 2014 · An anti-phospho-IRF7 antibody was used for detection of phosphorylated form of IRF7. IRF7 was present predominantly in an unphosphorylated form in cells transfected with IRF7 alone . Co-expression of MyD88, TRAF6 and IKKα enhanced the level of phosphorylated IRF7, whereas this enhancement was strikingly suppressed by co … inciweb historyWebJan 8, 2024 · (E, F) Flow cytometry analysis of phospho-IRF7 in CAL-1 WT and zDHHC2 −/− cells after gardiquimod stimulation. (E) Representative histogram of IRF7 phosphorylation level at 60 min after gardiquimod stimulation. (F) MFI of phospho-IRF7 at 0, 60, and 90 min after gardiquimod treatment, compared between WT and zDHHC2 −/− cells (n = 3, mean ... inbox ccof.orgWebIRF7 Antibodies Antibodies that detect IRF7 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Flow Cytometry, Immunocytochemistry and ELISA. These antibodies target IRF7 in Human, Mouse, Rat and Zebrafish samples. inbox cd manteWeb环保商城会员企业上海邦景实业有限公司提供杂交瘤细胞；tbcd6规格, 细胞名称 杂交瘤细胞；tbcd6规格形态特性 淋巴母细胞样生长特性 半贴壁生长 特征特性 该细胞属保藏，其特征特性尚未公开。培养条件 inbox chaos hard pass