Witryna2 dni temu · Orthologous to human IRGM (immunity related GTPase M). [provided by Alliance of Genome Resources, Apr 2024] Other designations. immunity-related GTPase family M protein 1, LPS-stimulated RAW 264.7 macrophage protein 47, immunity related GTPase m1, interferon-gamma-inducible GTPase Ifggd3 protein, … WitrynaFigure 1 Hypothetical model for the involvement of miR-196 in the pathogenesis of Crohn’s disease. MicroRNAs (miRNAs, miR) 196 normally targets immunity-related GTPase family, M (IRGM) mRNA within RNA-induced silencing complex (RISC) for a negative regulation (left panel). The IRGM risk allele (IRGM*) mRNA lacks the binding …
免疫相关GTP酶家族M蛋白 - Wikiwand
WitrynaImmunity-related GTPase family M (IRGM) is a human protein highlighted for its contribution to autophagy upon inflammation and infections. Studies have shown that IRGM is involved in the development of several cancers. In the current study, we investigated expression of IRGM and gastric cancer. Levels of messenger RNA … WitrynaTo further understand the interactions between Zap-70, Src family kinases, and other T-cell proteins, we have examined the regulation of Zap-70 in the antigen-specific T-cell line BI-141. By analyzing derivatives containing an activated version of either p56lck or p59fynT, it was observed that the two Src-related enzymes augmented T-cell … shower room pikmin 2
Immunity-related GTPase M (IRGM) proteins influence the
WitrynaThe classic G-protein heterotrimer consists of three subunits: one Gα, one Gβ and one Gγ. The Gα protein is a catalytically active GTPase and, in its active conformation, interacts with downstream effectors to transduce signals. Gα proteins across the plant evolutionary lineage show a high degree of sequence conservation. Immunity-related GTPase family M protein (IRGM), also known as interferon-inducible protein 1 (IFI1), is an enzyme that in humans is encoded by the IRGM gene. IRGM is a member of the interferon-inducible GTPase family. The encoded protein may play a role in the innate immune response by regulating … Zobacz więcej Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Zobacz więcej • Laukens D, Georges M, Libioulle C, Sandor C, Mni M, Vander Cruyssen B, et al. (November 2010). "Evidence for significant overlap between common risk variants for Crohn's disease and ankylosing spondylitis" Zobacz więcej Witryna4 kwi 2024 · immunity-related GTPase family M member 2. Synonyms. Gtpi, Iigp2 Feature Type. protein coding gene. IDs. MGI:1926262 ... protein coding gene: Chr11:58090444-58113609 (+) 129S1/SvImJ: MGP_129S1SvImJ_G0018346: protein coding gene: Chr11:57879087-57906842 (+) A/J: MGP_AJ_G0018316: shower room niche